LAB 01Open access
Light & fluorescence microscopy
Follow the light path, acquire images, and diagnose focus, signal and sampling problems.
Open labA journey into the unseen
Small worlds.
Infinite wonder.
There is an extraordinary world
just beyond your sight.
Meet JANA. Your guide to the unseen.
Follow your curiosity from light to atoms.
01 / POROUS MICROSTRUCTUREIllustrative artwork · not a measured specimen
Scroll to change your perspective MICRO → NANO → POSSIBILITY
01 / Change your perspective
How small is small?
Five stops through scale.
A different way to see at every step.
JANA / SCALE NOTES
A cellular perspective.
A cell contains a world of structures. Fluorescence helps distinguish selected features by the light they emit.
Explore light & fluorescence ↗These are comparative illustrations, not a continuous microscope zoom or measurements from a specimen.
Loading the 3D view when it comes into view. You can explore scale using the controls.
02 / Make a discovery
A little focus.
A different world.
Move through a fluorescent specimen. Separate its channels. Notice what appears—and what disappears.
JANA asks
When a feature disappears, has it gone—or are you looking at a different depth?
A little focus changes everything.TRY IT
CONFOCAL / SYNTHETIC CELLSZ 0.0 µm0 µm3 µm
Move through depth. Watch structures sharpen, soften, or leave the optical section.
Same XY field · fixed display scale · synthetic teaching preview
01 Explore the instrument02 Practise with purpose03 Understand the image
03 / Follow the light
A microscope you can explore.
Open the shutter. Follow the light.
See what each component does.
Explore the LFM simulator’s interactive microscope.
Loads on demand. Drag to orbit; view controls are also available.
The fluorescence journey
- 01Light source & shutter
- 02Excitation filter & dichroic
- 03Objective & specimen
- 04Returning emission & detector
Generic teaching model adapted from the LFM simulator. Geometry and light paths are simplified; motion is enlarged for learning. This homepage preview does not capture images or change your lab session.
MICROSCOPY CONCEPTS / LESSON 01
Bigger isn't always clearer.
A complete lesson with JANA.
Predict. Experiment. Explain.
Magnification versus Resolution
Follow the light in 3D. Enlarge two fluorescent points, open the objective aperture, and discover what actually reveals detail.
Start the 3D lessonSAME 300 nm PAIR / 520 nm EMISSION
NA 0.40793 nmNA 1.20264 nm
A smaller Rayleigh reference distance means closer features can meet the criterion. Display zoom alone leaves it unchanged.
The first complete concept lesson. Further topics from magnification and calibration to aberrations and detectors will follow.
04 / From curiosity to practice
Five ways to see.
One place to learn, practise
and understand your measurements.
Foundations begins with Learn. You can choose any available mode below.
LAB 02Open access
Atomic force microscopy
Scan a surface and connect probe shape and feedback settings to the measured image.
Open labLAB 03Open access
SEM / FIB microscopy
Explore electron imaging, ion milling and virtual lamella preparation.
Open labLAB 04Open access
Transmission electron microscopy
Explore the column, specimen loading, beam alignment and image formation.
Open labLAB 05Open access
Optical profilometry
Reconstruct a surface from interference signals and measure step height.
Open labAll five online laboratories are public. Each lab opens in another tab so you can keep your current work. Assessments are available only where implemented; other labs include guided checks and review questions.
05 / New perspectives
The frontier keeps moving.
Selected research, 2024–2025.
New ideas are changing what we can observe.
Make the specimen bigger.
A single expansion step enlarged preserved cells and tissues about twentyfold in each dimension, revealing nanoscale biological details with conventional confocal microscopes.
Read the research — Single-shot 20-fold expansion microscopy, Nature MethodsNature Methods · Expansion microscopySee more. Expose less.
Rapid electron scanning and computational reconstruction revealed atomic details at fragile perovskite edges, showing what carefully controlled electron dose can make possible.
Read the research — Atomically resolved edges and defects in lead halide perovskites, NatureNature · Low-dose electron imagingA small change in balance.
A seesaw-shaped probe separated mechanical hinges from its reflective surface, improving deflection sensitivity and capturing proteins and DNA structures in liquid.
Read the research — Seesaw cantilevers for high-speed AFM, Nature CommunicationsNature Communications · Probe designThese are published research advances. They are not claims that MVLscope reproduces these methods.
Your next discovery starts with a question.
Stay curious.
Look closer.
JANA guides your journey, from first discoveries to in-lab practice.
JANA / DISCOVERY WINDOW
What would you look for?
01 / FLUORESCENCESYNTHETIC CELLS
What becomes easier to distinguish when you separate the signals?
Choose a channel to follow DNA or actin labels through the same synthetic cell field.
Illustrative cell outlines · not a measured specimen.